Wild Type iPSC-Derived Human Microglia (iMG)

Wild-type human iPSC-derived microglia (iMG) provide a physiologically relevant model for investigating neuroinflammation, neurodegeneration, and CNS immune function. Originating from yolk sac-like progenitors, these cells closely recapitulate the identity and function of native human microglia – unlike peripheral macrophage models.

Wild-type iMGs express canonical microglial markers including P2RY12, IBA1, CD68, PU.1, CX3CR1, and CD33, and exhibit robust phagocytic activity. Cells are assay-ready five days post-thaw, with >85% purity and viability, and integrate seamlessly into 2D co-cultures or microphysiological systems. Each lot undergoes rigorous quality control for sterility, identity, and functionality to ensure consistent performance across experiments.

Available with supporting documentation and optional RNAseq data, wild-type iMGs enable reliable modeling of neuroimmune mechanisms and disease-relevant pathways involved in Alzheimer’s, Parkinson’s, Huntington’s, and ALS research.

FORMAT: Frozen

CELL TYPE: iPSC-Derived Human Microglia


SPECIES: Human


CELL AND TISSUE SOURCE: iPSC


DONOR STATUS: Normal